Silva converted Kevin de Bruyne's brilliant pass from close range in the 83rd minute as City maintained their blistering form this season and won their 13th successive EPL game.
The Citizens have already secured their place in the next round after recording five wins in five games.
And, speaking at a pre-match media conference in Ukraine, Toure - who also worked with Guardiola at Barcelona - said: "Our team is practising the best football in Europe but we want to play against the best teams to see where we are".
City finally threatened when teenage substitute Brahim Diaz scampered down the left only for his cross to be touched onto the post by Jesus.
The Spain international was simply outstanding, making an astonishing 14 saves - the highest ever in the Premier League - which is a number you would normally expect from a keeper playing for a side in the relegation zone against a top of the table side, and definitely not what you'd imagine in a meeting between two of the Premier League's top sides.
Instead, the club have been looking for a replacement full-back and with January fast approaching, they're confident of landing long-term target Danny Rose. "We are going to try to be who we are", he said.
"We came here to win, we couldn't but we were trying until the end to do so". He was brilliant for 75 minutes of that game, dominating the midfield and controlling everything United did. Great play from Marlos again to carry the attack to City, he lays it off for Bernard, who takes his time, waits for his moment, pulls the ball onto his right foot, before curling a sublime effort over Ederson and into the net.
After another incident packed weekend of football, it's time to reveal 5 things we learned in Premier League game week 15. There is much excitement about Foden's potential around the Etihad campus.
He won the Premier League with Mourinho then claimed to have experienced something different with current coach Conte, hitting back at his two previous coaches.